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Differences between primary and secondary substernal goiter Origin Blood supply Connection with cervical thyroid gland Cervical mass Primary From ectopically located tissue in chest Intrathoracic aorta None None Secondary Extension of normally located cervical thyroid gland into the chest Inferior thyroid artery Yes- usually contiguous with the cervical gland or may be connected with a fibrous band 80-90 of patients will have associated cervical mass Table 3.
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